To Study the Serum Cholesterol Levels in the Patients of Sepsis and Prognostic Significance

ABSTRACT

Introduction: Sepsis is today’s overwhelming and lifethreatning response to infection and recent studies reveal thatserum cholesterol may be a useful prognostic marker of sepsis.Aim: To study the serum cholesterol levels in the patients ofsepsis and its prognostic significance.Material and methods: This was an Prospective Observationalstudy done at CSS Hospital, SVSU Subharti Medical CollegeMeerut U.P. 100 Patients qualifying by fulfilling all inclusionand exclusion criteria and were enlisted in the study afterinformed consent. Serum cholesterol levels were done on theday of presentation and the 3rd day.Result: In the instant study, out of 100 subjects, 48 showedthe rise in the cholesterol with sepsis where as in 52 subjectsshowed decline of cholesterol level. During the study, 52subjects survived whereas 43 subjects expired during thecourse of treatment, 5 subjects left the study group.Conclusion: Monitoring the total cholesterol level can beused as prognostic tool in ICU patients. The level of totalcholesterol at the time of presentation and then the trendwhich is followed by the total cholesterol (increasing trendin total cholesterol level indicates better prognosis of diseaseoutcome and vice versa), is a better marker for prognosis ofthe patient with septicemia in ICU patients