Changes in Cardiorespiratory Parameters during the Management of status Epilepticus in Children: A Prospective Randomized Controlled Study

ABSTRACT

Introduction: Status epilepticus is a common pediatricneurological emergency. Study aimed to compare changes inhemodynamic parameters during the management of pediatricstatus epilepticus using different first line anticonvulsants.Material and Methods: This prospective, randomized, studywas done on Pediatric patients in the age group of 2 monthsto 16 years who present actively convulsing to the emergencydepartment of pediatrics.Results: The mean time to regain consciousness in phenytoin,levetiracetam and valproate groups was 122.3(± 45.4) minutes,120.8(±42.8) minutes and 75.0(±30.7) minutes (mean±S.D)respectively. There was no significant difference in the threegroups in various vital parameters like heart rate, systolicblood pressure, spo2 and respiratory rate recorded at regularintervals in the acute stage (p value > 0.05).Conclusion: All the three anticonvulsants studied are safeand efficacious, and there is no significant difference inthe cardiorespiratory parameters of three groups, and thetime to regain consciousness was less in valproate group incomparison to other groups