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Chronic Acquired Hepatocerebral Degeneration: A Case Report
Article | IMSEAR | ID: sea-202537
ABSTRACT

Introduction:

Chronic acquired hepatocerebral degenerationis a rare disorder typically accompanied by cognitivedisturbances and parkinsonian features secondary to liverdisease. It is the deposition of manganese in the basal ganglialeading to T1 hyperintensity on MRI of these patients and theresulting clinical features. Familial association is found insome cases.Case report Here, we report the case of a 32 year old postpartum female who presented with tremors and historyof liver disease. MRI of the brain showed symmetrichyperintensities in globus pallidi, substantiae nigrae, andsuperior cerebral peduncles in T1-weighted images. Althoughliver transplantation is the best modality of treatment atpresent, the patient showed improved on treatment withLevodopa+carbidopa.

Conclusion:

It is important to recognize this disease entity forsymptomatic relief of the patient. However further research isrequired for better management.

Full text: Available Index: IMSEAR (South-East Asia) Year: 2019 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Year: 2019 Type: Article