Comparative Study of 0.1%Ropivacaine-Fentanyl with 0.1%Bupivacaine-Fentanyl Given Epidurally for Labour Analgesia

ABSTRACT

Introduction: Addition of fentanyl to bupivacaine orropivacaine in epidural space will increase duration andquality of analgesia with similar safety profile. Study aimed tocompare epidural Inj. Bupivacaine 0.1% + Inj. Fentanyl andInj. Ropivacaine 0.1% + Inj. Fentanyl for onset, effectivenessand duration of analgesia, to study motor blockade intensity,to study hemodynamic parameters, to study technical anddrug related complications in mother and baby and to studyacceptability of technique by patient.Material and methods: A prospective interventional studywas conducted on 50 adult females with primigravida /multigravida full term pregnancy for epidural analgesia underASA 1 & 2. Unpaired Student t test was used to interpret theresults.Results: Patients got more pain relief and satisfaction withropivacaine+fentanyl as compare to bupivacaine+fentanyl.Conclusions: Addition of fentanyl to bupivacaine orropivacaine in epidural space increase duration and qualityof analgesia with similar safety profile and reduce therequirement of local anesthetic drugs during labour. It didnot hamper ambulation and bearing down of patient and hadsimilar incidence of maternal and fetal outcome, with goodpatient satisfaction.