Eccrine Skin Adnexal Tumors: An Institutional Based Clinicopathological Study

ABSTRACT

Background: Histopathology is the gold standard of diagnosiswith a limited role of Immunohistochemistry. The present studywas Conducted to study the Eccrine skin Adnexal tumors withreference to their Anatomical location, age, sex of theindividuals affected to determine their incidence and correlatethem with other simulating studies.Material & Method: A total of 106 specimens of skin Adnexaltumors were received in the department of pathology fromdepartment of Dermatology, surgery and other specialties fromJune 2002 to May 2012. Histopathological Examination wasdone on routine Hematoxylin and Eosin stained tissuesections. Special stains like PAS and recticulin was donewhere required.Results: There were 21 males and 25 female patientsconstituting a ratio of 0.841. The age range of these tumorswas 31-40 years with a mean age range of 43.73 years. In thepresent study 46/106 (43.39%) cases of SAT’s were of eccrinedifferentiation. Eccrine Acrospiroma was the most CommonBenign Skin adnexal tumor of Eccrine differentiationconstituting 25 out of 46 cases (54.34%) and Eccrine poromawas the least common benign Eccrine SAT. Out of 6 cases ofMalignant Eccrine skin Adnexal tumors 3/46 were of malignanteccrine acrospiroma and eccrine ductal carcinomarespectively.Conclusion: We concluded that the pattern and biologicalbehaviour of the tumors cannot be determined until thebiopsies are submitted for HPE so histopathology is mandatoryfor diagnosis SAT and to know their potential biologicalbehaviour for further management.