Study of Lipid Profile in Obese Persons with Type 2 Diabetes Mellitus

ABSTRACT

Introduction: Diabetes is a universal endemic with fastincreasing prevalence in both developing and developedcountries. Obesity is an unnecessary accumulation of body fatand in its gross manifestation possesses a real hazard tohealth. It is well recognized that obesity is directly or indirectlyassociated with type 2 diabetes mellitus. The aim was tocompare lipid profile in Type 2 diabetics with obesity and nondiabetic obese subject.Materials and Methods: This study was conducted inDepartment of Physiology, S.P. Medical College and Hospital,Bikaner, Rajasthan during the period from March 2015 toFebruary 2016. Weight was record in kilograms with thesubject standing on the weighing machine without shoes andmini-mum clothing.Results: Present study showed that the obese T2DM patientshad significantly higher serum triglycerides, LDL-C levels andserum VLDL-C levels; with significant lower HDL-C levels whencompared to obese non diabetic cases. Total cholesterol levelswere increased without significant ‘p’ value.Conclusion: We conclude that all the lipid fractions (exceptHDL-c) are strangely elevated in obese type 2 diabetics whencompared with obese controls.