Impact of Serum Total IgE and Disease Severity in Patients with Allergic Asthma: NIDCH in Dhaka

ABSTRACT

Objective: In this study our main aim is to evaluate impact ofSerum Total IgE and Disease Severity in Patients with AllergicAsthma.Method: This cross-sectional study was conducted at NIDCH,Mohakhali, Dhaka from one year (July 2012 - June2013).Among 150 asthma patients, 50 mild asthma patients, 50moderate and 50 severe asthma were selected in this study.Result: In our study among 150 patients, patients with midasthma belong to 15-19 years age group, where as patientswith moderate asthma and severe asthma belong to 25-29years and 35-39 years age group.21% patients with mildasthma unusually visit for regular checkup to doctor whereas48% patients with moderate asthma unusually visit regularly todoctor.47% patients with severe asthma level had >400 IU/mLserum level where as 19% patients with moderate asthma had>400 IU/mL serum level.Conclusion: From our study we can conclude that, serum totalIgE levels in adult patients with persistent allergic asthma fromBangladesh were high (two-thirds with levels >150 IU/mL) andvaried significantly. Further study is highly appreciated forbetter outcome.