Study of Uric Acid in Patient with Acute Myocardial Infarction

ABSTRACT

Introduction: Hyperuricemia is usually defined as increase inserum uric acid level which should be at least above 6mg/dl inwomen and at least above 7mg/dl in men. It has been revealedthat uric acid induces endothelial dysfunction by activating theHMGB1/RAGE signaling Pathway.Methodology: In this case- control study 100 total number ofpopulation were included. This study was conducted in theDepartment Of Medicine, C. U. Shah Medical College, Gujarat,India. The duration of study was over a period of six months.Results: In the present study, 26 cases & 25 control hadsystemic hypertension, 34 cases & 32 control had diabeticmellitus & serum uric acid level 7.272 in cases & 5.916 incontrol were seen.Conclusion: This study concludes that, SUA levels werehigher in patients with acute MI in comparison to normalhealthy individuals. In patients with acute MI, SUA levels areelevated in systemic hypertension and diabetes mellitus. Inacute MI patients, SUA can be used as a marker of short-termmortality. Hyperuricemia is found an indicator of poor prognosisin acute MI