Epidemiology of Thyroid Dysfunction in Patients Evaluated By TFT at a Tertiary Care Lab in Central India

ABSTRACT

Background: Thyroid abnormality is the most commonendocrinological problem encountered in day to day practice.Clinicians request for thyroid tests in patients with presence orabsence of clinical features. Results of thyroid assessment aresuggestive of hypo or hyperthyroidism. The categories ofthyroid dysfunction are subclinical and overt disease.Materials & Methods: The study was carried out at SSIMScentral clinical lab- biochemistry section. The design of thestudy was retrospective. Serum samples of patients weretested within 1 hour of sample collection using CLIA CL-1000iimmunoassay.Results: Higher prevalence rates of TD were found amongpatients aged 21 and 44 (61.0%) followed by those between 45and 64 years 17.91% and 12.69% among those aged 15 yearsand below. The difference in the frequency of ThyroidDisorders among age groups is statistically significant(p<0.001). Shows the pattern of thyroid disease whenscreened with Thyroid stimulating Hormone (TSH), maximumbeing subclinical.Conclusion: Thyroid dysfunction is a fairly commonabnormality in clinical practice. The spectrum comprises ofprimary (overt) and subclinical conditions.