The Risk Factor Associated with Relapse in Childhood Nephrotic Syndrome

ABSTRACT

Objective: In this study our main goal is to evaluate the riskfactor associated with Relapse in Childhood NephroticSyndrome.Methodology: This Cross-sectional comparative studyconducted at Tertiary Medical College Hospital, Dhaka fromJanuary 2017 to December 2018. During the study, 100 studysubjects were included with relapsed NS out of them 50 havingFRNS (Group-A) and 50 having IFRNS (Group-B) were takenusing simple random sampling technique.Results: During the study, most of the patients in group-A andgroup-B belongs to ≥ 5 Years age group, 61% and 64 %.).Only 25% patients were completed their graduation and mostof them belong to poor economic condition. Chi-square testrevealed no statistically significant differences between therelapsed and non-relapsed groups were seen in hypertension,infection, serum creatinine level, or hematuria. However, astatistically significant difference in subjects’ nutritional statuswas observed between the relapsed and non-relapsed groups(P=0.02).Conclusion: Nutritional status of patients at the time ofdiagnosis can be used as risk factor for relapse in pediatricnephrotic disease. Clinicians should provide nutritional therapyif the NS patient is poorly nourished and reevaluate at least sixmonths after steroid therapy.