Study of Acid Base and Electrolyte Disturbances in Patients of Acute Myocardial Infarction

ABSTRACT

Introduction: Myocardial infarction is the main cause of deathin Western countries, with in hospital mortality of 6-13%. Acidbase and electrolyte status in AMI patients at the time ofadmission that can be help in risk stratification and it can helpfor further planning of management strategy for managementof patient with AMI.Aim of Study To Study of Acid base and electrolytedisturbances in patients of acute myocardial infarction andrelation of Hypokalemia and hypomagnesemia with ventricularArrhythmias in AMI.Materials and Methods: This Observational study wasconducted in the department of Medicine at R.N.T. MedicalCollege and Govt. MB Hospital, Udaipur. Study subjects were50 patients of acute ST segment elevated Myocardial Infarctionpresenting within 24 hrs of onset of chest pain. We estimatedtheir acid base status, serum sodium, serum potassium, serummagnesium.Results: The definite correlation was found between metabolicacidosis and mortality (p=0.03). There was also increasedmortality in patients with hyponatremia, but p value was notstatistically significant (p=0.15). In our study definite correlationfound between hypokalemia and ventricular arrhythmias andalso between hypomagnesemia and ventricular arrhythmiasthere was increased tendency towards developing ventriculararrhythmias in patients with hypokalemia andhypomagnesemias. There was no correlation found betweenhypernatremia and mortality and between increased potassiumlevel and ventricular Arrhythmias in our study