Potency Of Γ-Oryzanol-Rich Black Rice Bran (ORYZA Sativa L. Indica) Extract For Tyrosinase Inhibition
Int J Pharm Pharm Sci
;
2020 May; 12(5): 85-89
Article
| IMSEAR
| ID: sea-206099
ABSTRACT
Objective:
The objectives of this study were to quantify γ-oryzanol in an ethanolic extract of Oryza sativa L. Indica (black rice) bran and to evaluate its activity as a tyrosinase inhibitor.Methods:
Black rice bran was extracted via maceration in 96% ethanol, and the γ-oryzanol concentration in the extract was measured through high-performance liquid chromatography. The applicability of the extract as a skin lightening agent was determined by evaluating its tyrosinase inhibition activity.Results:
The dry rice bran contained 118.572 mg/g of γ-oryzanol, and the extract inhibited tyrosinase activity at an IC50 of 74.8%.Conclusion:
The black rice bran extract was sufficiently potent for use in skin lightening formulations.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Journal:
Int J Pharm Pharm Sci
Year:
2020
Type:
Article
Similar
MEDLINE
...
LILACS
LIS