Production of a new antibacterial antibiotic from a mutated strain of Streptomyces kanamyceticus M27 in submerged fermentation.
Hindustan Antibiot Bull
;
2005-2006; 47-48(): 1-6
Article
in English
| IMSEAR
| ID: sea-2082
ABSTRACT
A new antibacterial antibiotic was produced (136.5 microg/ml) using a 5 L EYELA Fermenter using 2 L fermentation medium at temperature 27 degrees C, pH 7.2, agitator speed 200 rpm, aeration rate 1 vvm having KLa 251.74 hr(-1) at 96 hrs. The optimised conditions for antibiotic using washed cells of the selected strain are pH 7.2, temperature 27 degrees C, age of the biomass 72 hr, amount of washed cell 4 g in 50 ml normal saline, incubation time 72 hr. The antibacterial activity of the fermented broth was also examined against some bacterial species and it was found that it is active against gram positive as well as gram negative bacteria.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Streptomyces
/
Bacteria
/
Industrial Microbiology
/
Biomass
/
Fermentation
/
Anti-Bacterial Agents
Language:
English
Journal:
Hindustan Antibiot Bull
Year:
2005
Type:
Article
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