Comparison Of Intrathecal Nalbuphine With Different Doses Of Bupivacaine In Infraumbilical Surgeries

ABSTRACT

Background: Subarachnoid block (SAB) is a widely used regional anesthetic technique for infraumbilical surgeries.Aims: The study was conducted to compare intrathecal nalbuphine with different doses of bupivacaine in infraumbilical surgerieswith respect to hemodynamic changes, side effects, onset and duration of sensory as well as motor blockade, and duration ofanalgesia.Materials and Methods: After obtaining Institutional Ethics Committee approval, a prospective study was conducted on90 patients belonging to American society of Anesthesiology Grades I and II, aged 18–60 years and scheduled for infraumbilicalsurgeries using SAB. Three Groups A, B, and C each with 30 patients were given 0.8 mg nalbuphine along with 10, 12.5, and15 mg of hyperbaric bupivacaine, respectively.Statistical Analysis: Chi-square and unpaired “t” test and following results were observed.Results: Mean onset of sensory block until T10 dermatome was 2.59 ± 0.43, 2.49 ± 0.30, and 2.44–0.33 min while its totalduration was 102.23 ± 5.81, 110.10.83 ± 83, and 136.33 ± 6.15 min in Groups A, B, and C. Maximum motor blockade wasachieved in 7.55 ± 0.57, 7.41 ± 0.51, and 7.30 ± 0.62 min and mean duration of motor block was 145.27 ± 11.80, 155.00 ± 11.58,and 188.00 ± 10.27 min in Groups A, B, and C. Mean time of total duration of the analgesia in Groups A, B, and C was 240.83 ±36.34, 413.77 ± 68.60, and 719.90 ± 99.93 min. Patients in Group C had hypotension at 8th and 10th min intraoperatively whileother parameters and side effects were non-significant.Conclusion: About 0.8 mg of nalbuphine when combined with 12.5 mg of hyperbaric bupivacaine had optimum duration ofanalgesia and sensory block with lesser hemodynamic alterations and side effects.