Prevalence of Vitamin D Deficiency and its Effect on the Glycemic Control and Lipid Profile among Type 2 Diabetes Mellitus Patients in a Tertiary Care Hospital

ABSTRACT

Objective: The objective of the study was to find out the prevalence of Vitamin D deficiency among patients with type II diabetesmellitus (DM) and to assess the effect of Vitamin D in the control of blood sugar and lipid profile among patients with type 2 DM.Material and Methods: Study setting: This study was conducted at diabetic clinic, Chennai Medical College Hospital andResearch Centre, Irungalur, Tiruchirappalli. Study design: The present study was a hospital-based analytical cross-sectionaldesign. Sample size The sample size was taken as 90 (using the formula 4pq/l2). Analysis: The data collected were entered andanalyzed using the SPSS software package (Version 21). Descriptive statistics (mean, standard deviation and 95% confidenceinterval) and appropriate tests of significance (ANOVA) were applied to establish the relationship between the study variables.P < 0.05 was considered to be statistically significant.Results: We found that there was a significant reduction in all the glycemic indicators over the progressive weeks among thegroup of participants receiving Vitamin D supplements. We have also reported a uniform reduction in all the lipid profile valuesand glycemic indicators across all the three groups in the progressive weeks, with a significant reduction in the group receivingVitamin D supplements.Conclusions: Vitamin D supplementation improves glycemic control and can reduce or prevent the development of insulinresistance in type 2 diabetes mellitus patients. Considering the multitude of diseases associated with Vitamin D deficiency,increasing the population’s awareness of the beneficial effect of Vitamin D on health will be an important strategy overall.