Nature of Disordered Sleep in Patients with Moderate to Very Severe Chronic Obstructive Pulmonary Disease

ABSTRACT

Introduction: Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the world. Comorbiditiesoccur frequently in COPD patients.Aim: The present study was an observation based cross-sectional prospective study carried out with an aim to evaluate thebreathing disorders during sleep in patients with COPD and to correlate this disorder with the stage of the disease.Materails and Methods: A total of 50 patients were eligible for participation in our study. 18 patients had moderate COPD,19 patients had severe COPD, and 13 patients had very severe COPD as per the global initiative for chronic obstructive lungdisease guidelines.Results: Mean sleep efficiency was low at 53.25 ± 18.15. Sleep latency was normal in three patients only. We found abnormalsleep architecture in all three groups with decreased duration of stage N3 and stage rapid eye movement. Obstructive sleepapnea (OSA) was present in 23 of 50 subjects of COPD (Overlap syndrome).Conclusion: In present study, it was found that OSA is highly prevalent in patients with moderate to very severe COPD. Sleepquality is also poor among this selected group.