Phytochemical Screening and Larvicidal Activities of Some Ethnobotanicals from North Eastern Nigeria against Culicine (Dipera: Culicidae) Mosquito

ABSTRACT

was led on 423 Type II diabetic patients going to diabetic facilities at emergency clinics in Addis Ababa. Study members were chosen by utilizing orderly arbitrary examining procedure. A pre-tried organized survey was utilized to gather the information. Understanding Activation Measure (PAM-13) was utilized to survey tolerant actuation levels. Information were entered and dissected utilizing SPSS rendition 23 for windows. Concentrate members' qualities were portrayed as far as mean (Standard deviation) and recurrence (extent). Bivariate examination and various calculated relapse investigations were completed to recognize free factors related with patient enactment among sort II diabetes patients. Results:The mean (SD) age of the study participants was 55.7(±9.8) years. Majority of the study participants, 319 (77.8%) had low meal planning knowledge, 62.4% of patients involved in low physical activity and 82.2% had poor glycemic control. About 75.6% of the patients had low activation and the remaining 24.4% had high activation. The independent factors associated with lower activation were Illiterate educational status (AOR=2.4, 95% CI 1.5-3.3), low physical activity (AOR=1.8, 95% CI 1.4-2.9), low meal planning knowledge (AOR=1.5, 95% CI 1.3-2.4), chronic comorbidities (AOR=2.1, 95% CI 1.6-3.9) and poor glycemic control (AOR = 4.2, 95% CI 2.4–7.5).Conclusions:The findings revealed that majority of diabetic II patients had low activation; indicating patients had low knowledge and understanding regarding the influence of lifestyle in diabetes management. Illiterate educational status, low physical activity, low meal planning knowledge, chronic comorbidities and poor glycemic control were significantly associated with lower activation ether extracts with LC50(100.25, 115.53, 145.88, 68.44, 114.55, 46.79, and 175.07ppm).The larvicidal effect of individual isolates of alkaloids, tannin, saponins, azadirachtin, phenol and steroids demonstrated larvicidal potentials against 3rdinstar larvae ofculicine, where, terpenoids, flavonoids and glycoside showed no larvicidal potentials against culicine larvae. The larvicidal potential of each plant depend on the number of active ingredients and quantity available in each extract.In conclusion, the present plant extracts have potentials for development of new and safe control products for culicine mosquitoes.