Improved method for study of chromosomes of chorionic villus samples.
Article
in English
| IMSEAR
| ID: sea-20993
ABSTRACT
Chorionic villus sampling (CVS) offers rapid prenatal diagnosis of chromosomal disorders. We evaluated four methods for chromosomal analysis of chorionic villi (three based on direct preparations and one on long-term culture) in order to define a method which would provide good quality metaphases in sufficient numbers. The direct culturing method using synchronisation and dissociation with dispase was as good as long-term culturing. The optimal period of gestation for study was 10-12 wk.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Time Factors
/
Female
/
Humans
/
Pregnancy
/
Chorionic Villi Sampling
/
Chromosome Mapping
/
Cytogenetics
/
Evaluation Studies as Topic
Type of study:
Diagnostic study
/
Evaluation studies
Language:
English
Year:
1996
Type:
Article
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