Effect of Antiasthma Medication on Blood Eosinophil Count and Serum Immunoglobulin E Levels: A Randomized Controlled Study
Article
| IMSEAR
| ID: sea-210364
ABSTRACT
Background:
Asthma is a chronic inflammatory condition of lung airways resulting in episodic airflow obstruction.Aims:
The main objective of this study is tofind the effect of antiasthma medication on serum IgE levels and blood eosinophil count.StudyDesign:
Thisrandomizedcontrolled trial studywas performed in children aged 6-15 years of age, with clinically stable and moderate persistent asthma.Results:
The findings of this study indicate both group(Budesonide/formoterol group and budesonide group) patients experienced a significant decrease in serum IgE levels and blood eosinophil counts over the study period.However, the difference in two groups was not statistically significant.Conclusions:
Inhaled steroids are effective in controlling systemic inflammation in asthma as evidenced by a decrease in IgE levels and eosinophil counts. However addition of LABA doesn’t have any additive effect.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Controlled clinical trial
Year:
2020
Type:
Article
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