Candida auris: a bibliometric analysis of the first ten years of research (2009-2018)

ABSTRACT

Candida auris (C. auris) is an emerging multidrug resistant fungus considered as the cause of several nosocomialinfections of bad prognosis. This study presents a bibliometric analysis of global scientific research on C. auris sinceit was isolated first in 2009. A systematic search was conducted in Scopus databases in the period of 2009–2018 and atotal of 227 indexed documents were retrieved. A sharp increase in the number of studies related to drug and multidrugresistance of C. auris during 2016–2018 was observed, coinciding with an increase in the number of first-case andoutbreak reports worldwide. The leading countries based on the number of publications were United States, India,and the United Kingdom. Nevertheless, Netherlands ranked first when (i) ratio between the number of citations andnumber of publications, (ii) ratio between the number of publications and gross domestic product (GDP), and (iii) ratiobetween the number of citations and GDP were used as indicators of productivity. Despite the recent emergence of thetopic since the first-case report in 2009, recent research efforts have allowed identifying Ibrexafungerp (SCY-078) andRezafungin (CD101) as possible candidates for facing the actual antifungal resistance of C. auris.