Synergistic effect of allyl isopropyl acetamide with cadmium on hepatic heme synthesis in chick embryo.
Article
in English
| IMSEAR
| ID: sea-21110
ABSTRACT
The effect of cadmium along with a porphyrogenic drug, allyl isopropyl acetamide, on the induction of 5-amino levulinic acid (ALA) synthetase, ALA dehydratase and heme level was studied. The interaction of cadmium with allyl isopropyl acetamide indicated that the decrease in hepatic heme level by cadmium or allyl isopropyl acetamide may occur in a synergistic manner, whereas the induction of ALA synthetase by cadmium or allyl isopropyl acetamide may not take place in the same manner. Further, neither allyl isopropyl acetamide treatment alone nor allyl isopropyl acetamide-cadmium treatment had any effect on ALA dehydratase activity.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Cadmium
/
Chick Embryo
/
Dose-Response Relationship, Drug
/
Drug Synergism
/
Allylisopropylacetamide
/
Porphobilinogen Synthase
/
5-Aminolevulinate Synthetase
/
Heme
/
Liver
/
Animals
Language:
English
Year:
1989
Type:
Article
Similar
MEDLINE
...
LILACS
LIS