Fluorosis and its impact on thyroid hormones: a cross-sectional study in Bankura District, West Bengal, India
Article
| IMSEAR
| ID: sea-211359
ABSTRACT
Background:
Fluorosis is an important public health problem in India. Fluoride ions can interact with iodide which can leads to abnormal thyroid function.Methods:
The present descriptive, community based study was conducted over a period of 1 year and 6 months in the endemic and non-endemic areas of Bankura district with the sample size of 200. High serum fluoride level (≥0.02 mg/L) was also noted in fluorosis endemic areas (39%) with respect to non-endemic areas (3%). Thyroid profiles were investigated among the participants.Results:
Hypothyroidism was found to be higher in proportion in endemic regions (34%) with respect to non-endemic regions (20%). The levels of serum TSH, fT4 and fluoride in endemic areas were correlated significantly with non-endemic areas. Fluoride level was found to be in significant positive correlation with TSH level and in negative significant correlation with fT4 and fT3.Conclusions:
High fluoride level could produce hypofunctioning of thyroid gland and so hypothyroidism was found to be higher in proportion in fluorosis endemic areas in respect to non-endemic areas.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Observational study
/
Prevalence study
Year:
2019
Type:
Article
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