Drug use evaluation of vancomycin at medical ward of Yekatit 12, hospital medical college, Addis Ababa, Ethiopia, 2018

ABSTRACT

Background:Drug use evaluation is an ongoing systematic process designed to maintain the appropriate medication during & after dispensing in order to assure appropriate therapeutic decision making andpositive patient outcome. Methods:An institutional based cross-sectional study design was conducted to analyze drug use of vancomycin by using medication charts and medical note of patients that were admitted in the medical ward of Yekatit 12 Hospital Medical College. Data was analyzed using SPSS version 20. Patients who were admitted from medical ward and whose age were≥18years were eligible provided that they take Vancomycin during the study period were included and Patients with medical records of insufficient or illegible information’s were excluded. Structured check list was used for data collection, and the samplesize was 169. Convenience sampling technique was used.Results:Among 169 patients 136(80.5%) had empiric treatments, the remaining 33(19.5%) had specific treatments. Among 169 patients 61(36.1%) hadInfection during his/her stay in hospital of which 47(77%) were hospital acquired pneumonia, 169 patients 39(23.08%) had Vancomycin indication for hospital acquired pneumoniafollowed by 21 (12.4%), 21(12.4%), meningitis and PCP respectively. The finding indicated that only 135(79.9%) were appropriate regarding frequency, 124(73.4%) were appropriate regarding dose, 104(61.6%)were appropriate regarding duration, and the appropriate indication were only 128(75.7%).Conclusions:Vancomycinewas mostly indicated as empiric therapy and only 135(79.9%) were appropriately prescribed with respect to frequency, 128(75.7%) were appropriate regarding indication and 124(73.4%) were appropriate regarding to dose, 104(61.6%) were appropriate regarding to duration. All physicians should prescribe drugs according to the guidelines.