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Correlation of Mean Platelet Volume in Type 2 Diabetes Mellitus
Article | IMSEAR | ID: sea-215304
ABSTRACT
Diabetes mellitus is a major global health problem. It is classified as type 1 and type 2 diabetes. The disease and its complications also cause a heavy financial burden on diabetic patients, their families and the society. Mean platelet volume is a measurement of the average size of platelets and varies between 7.5 and 10.5 fl. We wanted to study the correlation of MPV and HbA1c.METHODSThe present study was conducted in the Department of Pathology, SSMC and SGMH, Rewa (MP) over a period of 18 months on 210 cases. Glucose was measured by GOD-POD method, MPV by cell counter and HbA1c by high performance liquid chromatography (HPLC) method. Unpaired t test is used to find out p value by using GraphPad software.RESULTSA total 210 cases were included. 60 cases were non-diabetic (Control Group) and 150 cases were of DMT2. The DMT2 group was further divided into DMT2 (controlled) and DMT2 (uncontrolled) on the basis of levels of HbA1c. MPV in DMT2 vs. non-diabetic was 10.80 ± 1.32 fl vs. 10.01 ± 1.12 fl respectively. MPV in DMT2 (uncontrolled) vs. DMT2 (controlled) was 11.07 ± 1.53 fl vs. 10.39 ± 0.75 fl respectively.CONCLUSIONSMPV in DMT2 patients was significantly higher than non-diabetic group. MPV in uncontrolled diabetic group (HbA1c >7%) was significantly higher than controlled diabetic group (HbA1c <7%). Hence MPV along with HbA1c can be a useful diagnostic test as well as prognostic marker of vascular complications in DMT2 patients.

Full text: Available Index: IMSEAR (South-East Asia) Year: 2020 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Year: 2020 Type: Article