Power divergence test statistics for testing Hardy–Weinberg equilibrium
J Genet
;
2019 Apr; 98: 1-6
Article
| IMSEAR
| ID: sea-215457
ABSTRACT
The Hardy–Weinberg equilibrium (HWE) model states that allele and genotype frequencies in a population will remain constant for generations in the absence of evolutionary effects. A goodness-of-fit test can be used to test if a population is significantly different from the expectations of HWE. Pearson statistics are commonly used in goodness-of-fit tests for testing the HWE. In this paper, a simulation study is carried out to evaluate the performance of power divergence statistics under different sample sizes, effect sizes and minor allele frequencies. A real genotype dataset is also analysed to compare the results of several power divergence test statistics.
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Index:
IMSEAR (South-East Asia)
Journal:
J Genet
Year:
2019
Type:
Article
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