Budleja asiatica Derived Phytochemicals against Eye Disease

ABSTRACT

The secondary metabolites in the plants are used for curing various diseases. The phytochemicals present in Budleja asiaticaplant extract are traditionally used to cure Eye disease. It is caused by Haemophilus influenza, whichis a facultatively anaerobic, gram-negative pathogenic bacteria. For analysis of ligand-protein interaction, the molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that lignoceric acid can effectively deactivate Aspararte semialdehyde dehydrogenase enzyme which is important macromolecule for the regulation of amino acid biosynthesis resulting in interrupting the life cycle of the microorganism