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Comparative study of brainstem auditory evoked responses in females having premenstrual symptoms with normal population
Article | IMSEAR | ID: sea-217776
ABSTRACT

Background:

Premenstrual symptoms (PMS) have largely been ignored, because ages so present study are done in females specifically having PMS comparing with females with no PMS. Very little work has been done in past in this field, because females revealing menstrual history are a big taboo in our society. Aim and

Objective:

The aim of this study was to study brainstem auditory evoked potential (BAEP) in females having premenstrual symptoms and comparing it with females having no premenstrual symptoms. Materials and

Methods:

BAEP was conducted on 60 females age group of 18–40 years in two groups in Research laboratory, Department of Physiology, Lala Lajpat Rai Memorial Medical College in collaboration with SVBP Hospital, Meerut for 6 months. The subjects were divided into two groups, Group A having premenstrual symptoms and Group B having no premenstrual symptoms. The test was conducted in later part of luteal phase 23rd–25th day of menstrual cycle. The absolute latencies (ALs) and interpeak latencies (IPLs) were the parameters measured for the analysis of BAEP.

Results:

IPL, that is, interpeak latencies I–III and III–V in age group 18–25 years, showed statistically significant decrease in luteal phase in females having premenstrual syndrome (PMS) as compared to normal cycling females.

Conclusion:

Premenstrual symptoms females are showing few significant changes in auditory responses at mid brain level as recorded by BAEP study which can be due to the modulatory effect of female gonadal hormones progesterone and estrogen on neurotransmitters (serotonin, gamma-aminobutyric acid, and glutamate) in central nervous system.

Full text: Available Index: IMSEAR (South-East Asia) Year: 2022 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Year: 2022 Type: Article