Comparison of Mammography, Sonography, Fine-Needle Aspiration Cytology, and Excision Biopsy for the Diagnosis of Breast Lesions

ABSTRACT

Background and Objective: Problem of invasive tests in breast lesion diagnosis can be addressed by comparing noninvasive tests with final Histopathological diagnosis obtained a?er excision biopsy. Present study was carried out to study diagnos?c u?lity of mammography, sonography, FNAC compared to excision biopsy for diagnosis of breast lesions Methods: Prospec?ve Observa?onal study was carried out among 81 women with Breast related symptoms. Digital Mammography Machine, ACUSON S3000TM Ultrasound System; FNAC and surgery for excision Biopsy were used. Sensi?vity, Specificity, Accuracy, Posi?ve and Nega?ve Predic?ve values were measured and p<0.05 was considered as sta?s?cally significant. Results: Sonography and FNAC composite have sensi?vity, specificity, accuracy, posi?ve and nega?ve predic?ve values 100.00%, 81.40%, 90.12%, 82.61% and 100.00% respec?vely. Mammography+FNAC (97.3%) is not as sensi?ve as Sonography+FNAC (100%), Sonography combined with FNAC is equally sensi?ve to excision biopsy (100%) and therefore can be used for screening purpose. Conclusion: Contrary to present guidelines which consider Mammography as most important screening tool for Breast Cancer, combina?on of Sonography and FNAC can be considered equally reliable.