Risk Factors and Predictors of Outcome for Necrotising Fasciitis

ABSTRACT

Background:Necrotising fasciitis(NF) is one of the most fulminant infec?on of skin and so? ?ssue. It is a fatal rapidly progressing disease causing Mul? organ Dysfunc?on syndrome (MODS), sep?c shock & death if not iden?fied early & treated accordingly. The aim is to study risk factors associated with NF and predictors of outcome. Se?ngs & design: Prospec?ve observa?onal study in a single ter?ary care center. Materials and Methods:Prospec?ve analysis of pa?ents with NF from March 2018 – August 2019 was done. The known risk factors were studied. Results: A Total 120 pa?ents were reviewed. Out of which 81 (67.5%) were males and 39 (32.5%) were females. The mortality rate in our study was 14.16%. It was significantly high in pa?ents with CRF (p 0.045), HIV (p <0.001), Diabetes with other risk factors (p 0.003),BSA > 10% (p <0.01), Type 3 culture (0.027),LRINEC score >6 (p 0.015). Conclusion:NF in pa?ents with known risk factors progresses rapidly, so aggressive treatment should be given at the earliest. Early iden?fica?on & prompt interven?on is the key for be?er survival outcome in NF.