Cytogenetic studies in ataxia telangiectasia & their use in prenatal diagnosis.
Article
in English
| IMSEAR
| ID: sea-21910
ABSTRACT
Cytogenetic studies were carried out in obligate ataxia telangiectasia (AT) heterozygotes, AT homozygotes and control subjects. Rate of chromosomal aberrations and the frequency of micronuclei were examined before and after radiation (100 rads). Significant differences in the rate of chromosomal aberrations and micronuclei were observed among heterozygotes, homozygotes and controls. The same methods were then applied for prenatal diagnosis of AT using amniotic cell culture in two families.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prenatal Diagnosis
/
Female
/
Humans
/
Pregnancy
/
Ataxia Telangiectasia
/
Child
/
Chromosome Aberrations
/
Micronuclei, Chromosome-Defective
Type of study:
Diagnostic study
Language:
English
Year:
1996
Type:
Article
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