Anesthetic Management in A Patient with Myasthenia Gravis Posted for Thymectomy

ABSTRACT

Myasthenia gravis is an autoimmune disease which causes disorder in transmission at the neuromuscular junction. In patients with myasthenia gravis undergoing surgical procedures administration of general anaesthesia becomes challenging. Overall safe general anaesthesia can be achieved through adequate preoperative assessment and optimization; vigilant intraoperative monitoring of neuromuscular transmission along with adequate dose titrations and by Train of four responses (TOF) guided administration of non depolarising muscle relaxants.