RETROSPECTIVE STUDY OF CHOLECYSTECTOMIES IN A TERTIARY CARE HOSPITAL FOR HISTOPATHOLOGICAL SPECTRUM OF GALL BLADDER DISEASES

ABSTRACT

Background: Gallstone is the most common disease of the gallbladder. The prevalence of gallstone disease varies with age, sex and ethnic group. Laparoscopic cholecystectomy is the treatment of choice done routinely for gallstone disease. Usually, the diagnosis given in most of the cholecystectomy specimens is quite straight forward; that is, chronic cholecystitis. Very rarely cholecystectomy specimen may reveal an unexpected gallbladder carcinoma This Methods: study is a hospital based retrospective study conducted in tertiary care hospital of Nagpur, Orange city hospital over a period of 5 years from 2017 to 2021. Clinical details and histopathology reports were obtained from surgery and pathology departments of hospital. Total 168 cholecystectomies were performed in 5 years. Results: During five year period 168 cholecystectomies were performed. Maximum number of patients were between 40-50 years ( 40.47%). There were 19% males and 81% females. Chronic cholecystitis was the predominant diagnosis (91%), followed by acute on chronic cholecystitis (4.7%), Gangrenous cholecystitis (2.3%) and adenocarcinoma of gall bladder (1.7%). Histopathological s Conclusions: pectrum of gall bladder specimen is extremely variable with chronic cholecystitis is most common diagnosis and prevalent in middle age female gender. Incidence of carcinoma is 1.7% in our study. Despite advances in diagnostic and surgical modalities, gallbladder cancer is still characterized by late diagnosis and poor prognosis except when incidentally diagnosed at an early stage after cholecystectomy for cholelithiasis. Hence, the histopathological examination of every cholecystectomy specimen is of utmost importance