Vaginal Estrogen Therapy in Postmenopausal Overactive Bladder

ABSTRACT

Objective: To assess the efficacy of vaginal estrogen therapy in postmenopausal overactive bladder (OAB). Study design: It is an OPD (outpatient department) based prospective study. Postmenopausal women attending gynecology OPD with complaint of OAB were enrolled for the study. Women fulfilling the criteria for the study were given estradiol 2 mg vaginal tablet everyday for 2 weeks, then weekly twice for 10 weeks. Patients were assessed by 3-day bladder diary, Patient Global Impression scale, before and after the therapy. Results: Ninety-three patients completed the study. Increased frequency of micturition was cured in 92.5% cases; urgency and urge incontinence was cured in 74.2% cases. Patient’s subjective feeling of improvement scale revealed only 12.9% women felt either no change or little better; rest all were happy. Conclusion: Local estrogen therapy in postmenopausal women with OAB resulted in a good outcome.