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Immunoreactivity with S100 protein as an indicator of pregnancy.
Article in English | IMSEAR | ID: sea-22267
ABSTRACT
The usefulness as a pregnancy marker, of immunoreactivity with S100 protein antiserum in endometrial curettings and fallopian tubes during pregnancy was assessed. Twenty six placental tissues of various gestational age, two hydatidiform moles and four fallopian tubes removed for ectopic pregnancy were stained with S100 protein polyclonal antiserum by immunoperoxidase technique. Strong immunostaining was found in glands within the decidua and epithelial cells of fallopian tubes during early pregnancy. However, no S100 protein could be demonstrated in the endometrium in various phases, endometrial carcinomas, decidual glands beyond 12 wk of gestation and normal fallopian tubes. The results indicate a relationship between S100 protein and early pregnancy. Positive immunoreactivity with S100 protein antiserum in the decidual glands and fallopian tube epithelium may help in confirmation of doubtful cases of pregnancy.
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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Placenta / Female / Humans / Pregnancy / Pregnancy Tests, Immunologic / Biomarkers / Hydatidiform Mole / S100 Proteins / Cervix Uteri / Immunoenzyme Techniques Language: English Year: 1992 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Placenta / Female / Humans / Pregnancy / Pregnancy Tests, Immunologic / Biomarkers / Hydatidiform Mole / S100 Proteins / Cervix Uteri / Immunoenzyme Techniques Language: English Year: 1992 Type: Article