Current approach to diagnosis of inflammatory myopathies: Clinical features and myositis antibody profiles
Indian J Pathol Microbiol
;
2022 May; 65(1): 252-258
Article
| IMSEAR
| ID: sea-223287
ABSTRACT
Diagnosis of inflammatory myositis has been made easier with the availability of commercial assays for myositis-specific and myositis-associated antibodies. Clinico-serological association studies have permitted a better definition of clinical subsets. Myositis-specific auto-antibodies are highly specific and non-overlapping, whereas myositis-associated antibodies are those seen also in other connective tissue disorders such as systemic lupus erythematosus, primary Sjogren's syndrome, and idiopathic pulmonary auto-immune fibrosis. Their value is pronounced when clinical features are subtle or non-specific or when the muscle is not the primary organ involved. Overall, the muscle-specific and myositis-associated antibodies have changed the landscape in terms of diagnostic utility, prognostication, and the approach to organ-specific evaluation and management of idiopathic inflammatory myopathies (IIMs).
Full text:
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Index:
IMSEAR (South-East Asia)
Journal:
Indian J Pathol Microbiol
Year:
2022
Type:
Article
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