Body fluids: Comparison of liquid based cytology with conventional cytopreparatory technique
Indian J Pathol Microbiol
;
2023 Mar; 66(1): 75-80
Article
| IMSEAR
| ID: sea-223389
ABSTRACT
Introduction:
In the diagnosis of malignant tumors, cytological examinations of various body fluids are useful. For the preparation of body fluid, many methods are used till date. The use of liquid-based cytology is new upcoming in the field.Aim:
To examine the performance of liquid-based cytology on body cavity fluids as compared to conventional cytopreparatory techniques.Methodology:
In the present study, 700 body fluid samples were processed by both liquid- based cytology (BD SurePath™) and conventional cytopreparatory technique (Thick & Thin). The performance of both techniques was compared in terms of “smear quality” and “overall diagnostic test performance.”Results:
Out of 155 body fluid samples from proven malignancy patients, 32 (20.65%) were reported as Positive for malignancy, 23 (14.84%) as Suspicious of malignancy, and 100 (64.51%) as Negative for malignancy by CS (Thick and Thin). A total of 44 (28.39%) were reported as Positive for malignancy, 12 (7.74%) as Suspicious of malignancy, and 99 (63.87%) as Negative for malignancy by LBC.Conclusion:
Liquid-based cytology is advantageous over conventional techniques in cytomorphology of body fluids, but not better in sensitivity and specificity. Also saves cytopathologist's valuable time for screening.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Journal:
Indian J Pathol Microbiol
Year:
2023
Type:
Article
Similar
MEDLINE
...
LILACS
LIS