Dengue and Scrub Typhus Co-infection in Children: Experience of a Teaching Hospital in an Endemic Area
Indian J Public Health
;
2022 Sept; 66(3): 292-294
Article
| IMSEAR
| ID: sea-223835
ABSTRACT
Background:
Dengue fever and scrub typhus are considered an endemic disease in the Indian subcontinent. The epidemiology and clinical presentations are complex and vary each year.?Objective:
The objective of this study was to estimate the prevalence of coinfection with scrub typhus in children diagnosed with dengue fever.Methods:
A retrospective hospital-based, cross-sectional study was done in the Department of Pediatrics of a teaching hospital in Puducherry. All children (0–14 years) who had enzyme?linked immunosorbent assay (ELISA) reported scrub typhus among those diagnosed with dengue fever (NS1Ag or immunoglobulin M ELISA positivity) during 2012–2016. Medical records with incomplete data were excluded from the study. Odds ratio was calculated to find out the association of coinfections. An independent t-test was used to find out the statistical significance. P < 0.05 was considered statistically significant.Results:
Atypical features of dengue were present in 250/318 (78.6%) children. Coinfections were seen in 62/318 (19.4%) children. Scrub typhus was the most common (n = 51/62, 82.2%). The chance of scrub typhus in a dengue serology?positive child is significant when the symptoms are atypical or protracted (OR– 2.6, P = 0.033).Conclusion:
High index of suspicion should be present in endemic dengue and scrub typhus coinfection.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Journal:
Indian J Public Health
Year:
2022
Type:
Article
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