Posterior corneal morphological changes in primary congenital glaucoma
Indian J Ophthalmol
;
2022 Jul; 70(7): 2571-2577
Article
| IMSEAR
| ID: sea-224432
ABSTRACT
Purpose:
To compare posterior corneal morphology between older treated and younger untreated children with primary congenital glaucoma (PCG) using anterior segment optical coherence tomography (ASOCT) and intraoperative OCT (iOCT), respectively.Methods:
In this comparative study, ASOCT of older PCG children were compared with iOCT of younger untreated PCG patients. Differences between the two groups with respect to posterior corneal morphology were studied.Results:
Observed morphological patterns within posterior cornea in older treated (age 72–300 months) children (87 eyes) included Descemet’s membrane (DM) excrescences (70%), thickened DM (35%), intracameral twin protuberances (92%), and DM detachment (26%). Changes within pre?Descemet’s layer (PDL) (28%) included thickening, breaks, and detachments. Extent of Haab’s striae was associated with thickness of DM/PDL complex (P = 0.008) when analyzed in the treated group. In contrast, in the untreated group (n = 53 eyes, age 1–63 months), posterior corneal changes were limited to diffuse hyper?reflectivity of the DM/PDL complex, with absence of DM tears.Conclusion:
Posterior cornea thickens and Haab’s striae become more circumscribed in eyes of older treated children compared to untreated PCG eyes, probably reflecting a healing response of posterior cornea over time.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Journal:
Indian J Ophthalmol
Year:
2022
Type:
Article
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