Hindi Translation and Validation of Childhood Asthma Control Test (C-ACT)

ABSTRACT

Objective: Hindi translation and validation of the Childhood Asthma Control Test (C-ACT). Methods: Children aged 5-11 years with newly diagnosed asthma were enrolled and followed every 4-weeks for 12 weeks. Asthma control was assessed with C-ACT and Global Initiative for Asthma (GINA) criteria. Results: 60 children (34 boys, 56%) were enrolled. C-ACT showed a statistically significant correlation with GINA criteria at all visits. Cronbach’s alpha to assess the internal consistency was 0.74, and the intraclass correlation coefficient to measure test-retest reliability was 0.83. The maximum area under the curve (AUC) for C-ACT was 0.95 (95% CI 0.89-1.0; P<0.001). At a cutoff score of ?20, the sensitivity, specificity, positive predictive value, and negative predictive value of C-ACT were 97.9%, 25%, 88.7%, and 87.5%, respectively. Conclusions: Hindi version of the CACT score is valid, reliable, and correlates well with the GINA criteria for asthma control in children. It has a high sensitivity at a cutoff score of ?20, but the specificity was poor in differentiating asthma control.