Role of bacterial flora in the pathogenesis & management of atopic dermatitis.
Article
in English
| IMSEAR
| ID: sea-23481
ABSTRACT
The carriage state of Staphylococcus aureus and its role in the pathogenesis and management of atopic dermatitis were evaluated in 50 patients, aged 3 months to 12 yr. An equal number of age and sex matched controls were also studied. The positivity of Staph.aureus in patients with atopic dermatitis was 50 per cent from eczematous skin, 34 per cent from anterior nares and 26 per cent from normal skin. In controls, the comparative figures were 14 per cent from anterior nares and 10 per cent from normal skin. After institution of oral erythromycin or cloxacillin therapy (according to sensitivity), the colony counts dropped to 18 per cent from eczematous skin, 14 per cent from anterior nares and 8 per cent from normal skin after one week and to zero after 3 wk. This was associated with significant clinical improvement. The results of this study suggest that Staph. aureus aggravates the eczematous process in patients with atopic dermatitis and antibiotics decrease the severity and are useful in long term prognosis of the disease.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Skin
/
Staphylococcal Infections
/
Staphylococcus aureus
/
Female
/
Humans
/
Male
/
Carrier State
/
Child
/
Child, Preschool
/
Dermatitis, Atopic
Type of study:
Etiology study
Language:
English
Year:
1992
Type:
Article
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