Class specific antinuclear antibodies in systemic lupus erythematosus.

Savitri, K; Sehgal, S; Datta, B N; Chugh, K S

Savitri, K; Sehgal, S; Datta, B N; Chugh, K S.

Article in English | IMSEAR | ID: sea-24203

ABSTRACT

ABSTRACT

The incidence and significance of class specific antinuclear antibodies (ANA), specially with relevance to clinical manifestations of arthritis, renal disease and serositis was studied in 40 patients of systemic lupus erythematosus by the indirect immunofluorescent method. Clinical activity was scored by Morimoto's scoring system. A significant correlation was obtained between IgD ANA and clinical activity of the disease and IgG ANA exhibiting lupus pattern of immunofluorescence and serositis.

Subject(s)

Antibodies, Antinuclear/analysis; Antibody Specificity; Fluorescent Antibody Technique; Humans; Immunoglobulin D/analysis; Immunoglobulin G/analysis; Immunoglobulin M/analysis; Lupus Erythematosus, Systemic/diagnosis; Lupus Nephritis/immunology

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Lupus Nephritis / Humans / Immunoglobulin D / Immunoglobulin G / Immunoglobulin M / Antibodies, Antinuclear / Fluorescent Antibody Technique / Lupus Erythematosus, Systemic / Antibody Specificity Language: English Year: 1993 Type: Article

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