Levels of erythrocyte malonyldialdehyde, vitamin E, reduced glutathione, G6PD activity & plasma urate in patients of pregnancy induced hypertension.
Article
in English
| IMSEAR
| ID: sea-24763
ABSTRACT
To assess the oxidative stress across the cell membrane in patients suffering from pregnancy induced hypertension, erythrocyte malonyldialdehyde, vitamin E, reduced glutathione, glucose-6-phosphate dehydrogenase activity and plasma urate levels were estimated in 25 non pregnant women, 40 normotensive pregnant women and 40 women with pregnancy induced hypertension (PIH). As compared to non pregnant women, there was a significant increase in the levels of erythrocyte malonyldialdehyde and plasma urate in normotensive pregnant women, which were further increased in women with PIH. Erythrocyte glutathione levels were raised in normotensive pregnant women as compared to non pregnant women. Its levels were decreased in patients of PIH as compared to normotensive pregnant women. Cellular bio-availability of vitamin E was depressed in both normotensive pregnancy as well as patients with pregnancy induced hypertension as compared to non pregnant women.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pre-Eclampsia
/
Uric Acid
/
Vitamin E
/
Female
/
Humans
/
Pregnancy
/
Oxidative Stress
/
Adult
/
Erythrocytes
/
Glucosephosphate Dehydrogenase
Type of study:
Controlled clinical trial
Language:
English
Year:
1994
Type:
Article
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