Immunoglobulin profile in acute psychiatric disorders.
Article
in English
| IMSEAR
| ID: sea-24860
ABSTRACT
In a prospective study of 80 new female patients with acute psychiatric disorders (40 each with schizophrenia and major affective disorder), elevated (P less than 0.001) serum concentrations of IgG and IgA were found in comparison to healthy control groups matched for age and sex. In schizophrenic patients the mean levels of IgG (1682.76 mg/dl) and IgA (321.12 mg/dl) were found to be significantly more as compared to those in the control group (IgG-1213.18 mg/dl and IgA - 210.14 mg/dl). Patients with paranoid schizophrenia had significantly high mean serum levels of IgG (1896.86 mg/dl) and IgA (376.16 mg/dl) in comparison to other subtypes of schizophrenia (i.e., catatonic, disorganized and undifferentiated). Mean serum concentrations of IgG and IgA in major affective disorder - mania (IgG 1526.36 mg/dl and IgA 382.16 mg/dl) and major depressive episode (IgG 2008.12 mg/dl and IgA 536.72 mg/dl) were found to be significantly higher as compared to those in the control group (IgG-920.21 mg/dl and IgA - 232.12 mg/dl).
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Osmolar Concentration
/
Female
/
Humans
/
Immunoglobulins
/
Acute Disease
/
Prospective Studies
/
Adolescent
/
Adult
/
Mental Disorders
Type of study:
Diagnostic study
/
Observational study
Language:
English
Year:
1990
Type:
Article
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