Effect of vitamin A deficiency on rat intestinal digestive & absorptive functions.
Article
in English
| IMSEAR
| ID: sea-25081
ABSTRACT
The effect of vitamin A deficiency on the intestinal absorption of nutrients and the activities of brush border enzymes were studied in albino rats. Intestinal uptakes of D-glucose, L-methionine, L-tryptophan and L-histidine were significantly greater in vitamin A-deficient animals than in controls. The specific activities of total adenosine triphosphatase (ATPase), ouabain-sensitive ATPase, maltase and sucrase in the intestinal mucosa of vitamin A-deprived rats were 121, 124, 131 and 134 per cent respectively, of the corresponding values in control animals. The DNA content of the small intestine in vitamin A-deficient rats was 36.5 per cent lower than in control rats. The stimulation in digestive and absorptive capacity appears to be an adaptive change in vitamin A-deficiency which decreases the intestinal cell population.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Rats, Inbred Strains
/
Vitamin A Deficiency
/
Adenosine Triphosphatases
/
Digestion
/
Glucose
/
Intestinal Absorption
/
Intestinal Mucosa
/
Animals
Language:
English
Year:
1989
Type:
Article
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