Resistance to activated protein C (APC) in Indian patients of thrombophilia.
Article
in English
| IMSEAR
| ID: sea-25586
ABSTRACT
In a pilot study, 28 consecutive patients with thrombosis and 23 age and sex matched healthy normal controls were investigated with normalised APC sensitivity ratio (n-APC-SR) to know the defect exists and if so its prevalence in India. Six of the 28 (21.4%) thrombotic patients had n-APC-SR of < 0.76 (range 0.55 to 0.74) as compared to the normal control value (0.97 +/- 0.105). Our study shows APC resistance defect in a significant proportion (21.4%) of Indian patients with thrombotic disorders.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thrombosis
/
Female
/
Humans
/
Male
/
Protein C
/
Case-Control Studies
/
Child
/
Adolescent
/
Adult
/
Disease Susceptibility
Type of study:
Observational study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Year:
1996
Type:
Article
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