Effect of ethanol ingestion on tryptophan metabolism in streptozotocin diabetic rats.
Indian J Biochem Biophys
;
1990 Oct; 27(5): 339-41
Article
in English
| IMSEAR
| ID: sea-26332
ABSTRACT
Ingestion of ethanol by albino rats affected brain liver and plasma tryptophan contents in both normal and diabetic animals, although at different rates. Liver tryptophan was increased in both the groups, whereas tryptophan levels in brain and plasma of normal group were decreased and those of diabetic group were increased after the treatment. Similarly, while hepatic tryptophan dioxygenase activity was decreased in both the groups, activity of hepatic 3-hydroxykynureninase was increased only in normal rats and that of liver picolinic carboxylase was significantly decreased only in the diabetic group after ethanol administration.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Rats, Inbred Strains
/
Tryptophan
/
Male
/
Diabetes Mellitus, Experimental
/
Ethanol
/
Kynurenine
/
Animals
Language:
English
Journal:
Indian J Biochem Biophys
Year:
1990
Type:
Article
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