Further studies on the influence of aminophylline on lipids of Microsporum gypseum.
Indian J Biochem Biophys
;
1993 Feb; 30(1): 71-2
Article
in English
| IMSEAR
| ID: sea-26481
ABSTRACT
Aminophylline added to the growth medium of Microsporum gypseum for varying periods exhibited varied effects on lipid synthesis. A decreased incorporation of [14C]acetate into both lipids and phospholipids was initially observed which showed increase after 24 hr of incubation. Short-time exposure of aminophylline also resulted in decreased activity of glycerol-3-phosphate acyltransferase, the key enzyme of lipid synthesis, which, however, got stimulated on longer incubation, supporting the decreased/increased synthesis of lipids during short/long time exposure. Changes in the intracellular levels of cAMP at different time points account for the induced alterations in lipid synthesis, possibly due to formation of metabolites of aminophylline during growth of the organism.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Cyclic AMP
/
Aminophylline
/
Lipids
/
Microsporum
Language:
English
Journal:
Indian J Biochem Biophys
Year:
1993
Type:
Article
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