Antibacterial activity of some unsymmetrical diorganyltellurium(IV) dichlorides.
Indian J Biochem Biophys
;
2005 Dec; 42(6): 398-400
Article
in English
| IMSEAR
| ID: sea-26564
ABSTRACT
Six unsymmetrical diorganyltellurium(IV) dichlorides RR'TeCl2 (where R= phenacyl-, 1-naphthacyl-, and styrylacyl- and R' = p-methoxyphenyl, p-hydroxyphenyl-, and 3-methyl-4-hydoxyphenyl-) were tested for their antibacterial activity against gram-positive (Bacillus subtilis ATCC 6633 and Staphylococcus aureus ATCC 25923) and gram-negative (Escherichia coli ATCC 25922. Pseudomonas aeruginosa ATCC 27853 and Salmonella sp.) bacteria. Antibacterial activity was measured by disk diffusion method. Inhibition zones demonstrated that all the compounds showed good activity against gram-negative strains. Phenacyl (3-methyl-4-hydroxyphenyl) tellurium(IV) dichloride and naphthacyl (3-methyl-4-hydroxyphenyl) tellurium(IV) dichloride showed significant activity against both gram-positive and gram-negative strains. Among the tested compounds, the former exhibited maximum activity against gram-positive bacteria, while the latter against all the bacteria under study and styrylacyl (p-methoxyphenyl) tellurium(IV) dichloride against all the three gram-negative bacteria.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pseudomonas aeruginosa
/
Staphylococcus aureus
/
Tellurium
/
Microbial Sensitivity Tests
/
Enterococcus faecalis
/
Escherichia coli
/
Anti-Bacterial Agents
Language:
English
Journal:
Indian J Biochem Biophys
Year:
2005
Type:
Article
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