Change of ADP-ribosylation in human kidney T1-cells by various external stimuli.
Indian J Biochem Biophys
;
1995 Jun; 32(3): 119-24
Article
in English
| IMSEAR
| ID: sea-26926
ABSTRACT
Human kidney T1-cells in culture respond to various externally applied stresses, such as mechanical manipulations, trypsinization combined with agitation and centrifugation, Gamma-irradiation, and hyperthermia, by increasing the ADP-ribosylation (ADPR) of proteins in cytoplasm and nuclei. On the other hand, a strong static magnetic field or gravitational force reduces ADPR of proteins. These responses are easily detected in cells in monolayer, yet are masked when the conventional assay of ADPR is used on cells in suspension. The multitude of stimuli for either increasing or depressing ADPR of proteins including histones suggests a common pathway of triggering ADPR in which cellular membranes may be involved.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Physical Stimulation
/
Humans
/
Cell Line
/
Adenosine Diphosphate Ribose
/
Kidney
Language:
English
Journal:
Indian J Biochem Biophys
Year:
1995
Type:
Article
Similar
MEDLINE
...
LILACS
LIS