Antidiabetic and hypolipidemic effects of S-methyl cysteine sulfoxide isolated from Allium cepa Linn.
Indian J Biochem Biophys
;
1995 Feb; 32(1): 49-54
Article
in English
| IMSEAR
| ID: sea-27384
ABSTRACT
S-methyl cysteine sulphoxide (SMCS), a sulphur containing amino acid isolated from onion (Allium cepa Linn) showed antidiabetic and antihyperlipidemic effects. Oral administration of SMCS daily at a dose of 200 mg/kg body weight for a period of 45 days to alloxan diabetic rats controlled significantly their blood glucose and lipids in serum and tissues and altered the activities of liver hexokinase, glucose 6-phosphatase and HMG CoA reductase towards normal. The above effects of SMCS were comparable to those of glibenclamide and insulin.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Allium
/
Male
/
Rats, Sprague-Dawley
/
Cysteine
/
Diabetes Mellitus, Experimental
/
Hypoglycemic Agents
/
Animals
/
Hypolipidemic Agents
Language:
English
Journal:
Indian J Biochem Biophys
Year:
1995
Type:
Article
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